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A clinician will typically start with a physical exam, and may order an ultrasound or blood tests to narrow down the cause

Sun Z, Chen Z, Liu R et al (2023) Research Progress on the efficacy and safety of spironolactone in reversing left ventricular hypertrophy in hemodialysis patients

Inflammopharmacology 25 (2), 255264

It has shown efficacy in animal models of inflammatory bowel disease (IBD), gastric ulcers, and "leaky gut." Systemic anti-inflammatory effects: It appears to dampen inflammatory cascades without the immune-suppressing risks associated with corticosteroids

Downregulation of miR-338-3p could lead to upregulation of GPX3, suggesting its potential as a novel therapeutic target for managing hypertension and vascular damage in CKD patients [95]